Brain Injury After Intracerebral Hemorrhage

نویسندگان

  • Ya Hua
  • Richard F. Keep
  • Julian T. Hoff
  • Guohua Xi
چکیده

Intracerebral hemorrhage (ICH) is a subtype of stroke with high morbidity and mortality. The mechanisms underlying ICH-induced brain injury have become better understood during the past decade. Experimental investigations have indicated that thrombin formation, red blood cell lysis, and iron toxicity play a major role in ICH-induced injury and that these mechanisms may provide new therapeutic targets. This article reviews the role of thrombin and iron in ICH-induced injury. (Stroke. 2007;38[part 2]:759-762.)

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تاریخ انتشار 2007